Increasing Platelet Concentration in Platelet-Rich Plasma Inhibits Anterior Cruciate Ligament Cell Function in Three-Dimensional Culture

Abstract The anterior cruciate ligament (ACL) is a key stabiliz-er of the knee that is prone to injury, especially inyoung, active women. The annual incidence of ACLrupture in the U.S. alone is 400,000.1Unlike otherligaments, such as the medial collateral ligament, theACL fails to heal even after suture repair. Therefore,the current standard of treatment for ACL […]